Endocrine Abstracts

Background: Bilateral micronodular adrenal cortical disease (miBACD) is a rare and difficult-to-manage disease. miBACD is one of the causes of Cushing’s syndrome. miBACD is divided into primary pigmented nodular adrenocortical disease (PPNAD) and isolated micronodular adrenocortical disease. Its more common presentation is familial PPNAD, as part of Carney syndrome. We also presented a rare case of miBACD.Case presentation: A 20-year-old female pati...

Hashimoto thyroiditis (HT) is the most common cause of hypothyroidism in the world with iodine deficiency and its incidence is 0.3–1.5 per 1,000. The aim of this study is to retrospectively evaluate the demographic characteristics, clinical and laboratory findings of the patients with HT who applied to our endocrinology outpatient clinic. The findings were compared with the control group who had hypothyroidism with negative thyroid autoantibodies. For this purpose, a tota...

Introduction: Pituitary apoplexy (PA) is a clinical emergency resulting from acute ischemia or bleeding of the pituitary gland. Complaints of patients are usuallay headache and vision problems. We tried to discuss the reasons for presentation, pituitary imaging and hormones of patients.Patients and Methods: 10 patients (5 men and 5 women), median age 53 years at diagnosis were retrospectively reviewed. FSH, LH, estradiol/testosterone, GH, IGF1, TSH, FT4,...

Acromegaly is a rare disease associated with hypersecretion of growth hormone due to adenoma of somatotroph cells in the pituitary gland, with elevated morbidity and mortality. Acromegaly and thyroid diseases show high co-occurrence. In our study; we aimed to determine the relationship between disease activity at the time of admission and after treatment with the presence of goiter, presence of nodules, and possible accompanying thyroid malignancy in 119 patients with acromega...

Introduction: Adrenal gland involvement can be seen in about 25% of lymphomas. However, primary adrenal lymphomas (PAL) are rare. The most common is diffuse large B-cell lymphoma (DLBCL). It is seen usually after the age of 60 years as bilateral, large masses.Case report: A 64-year-old woman with a complaint of abdominal pain was referred to our clinic after bilateral surrenal masses were detected upon abdominal ultrasonography (USG) and computed tomogra...

Introduction: Ganglioneuroma is an extremely rarely seen tumour in the adrenal gland, which originates from neural crest cells. Clinically, they generally have a silent course and in laboratory tests, the hormone levels expressed from the adrenal gland are within the normal range.Case: A 46-year old male patient, for whom a mass in the adrenal gland was diagnosed incidentally on abdominal ultrasonography and MRI. The physical examination, laboratory test...

Introduction and purpose: More than 90% of differentiated thyroid cancers are papillary thyroid cancer (PTC). Lymph node metastasis is common in PTC and has been reported to have no effect on prognosis. The risk of cervical metastasis is high in the presence of clinicopathologic factors including extrathyroidal extension, multifocality and lymphovascular invasion. In this study, it was aimed to evaluate the clinicopathological features of lymph node metastasis development....

Introduction: A significance of chronic hyperglycaemia related to the rising intraocular pressure are discussed in the previous studies. The purpose of the present study was to investigate changes of intraocular pressure induced by acute changes of glucose levels during oral glucose tolerance test in non-diabetic subjects.Methods: Fifty-one individuals who were needed to be screened for diabetes, were scheduled for oral glucose tolerance test according t...

Introduction: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessively inherited disorders that are characterised by inactivating mutations at various steps of adrenal steroidogenic pathways causing defective cortisol biosynthesis. 21-Hydroxylase enzyme deficiency (21-OHd) constitutes more than 95% of all CAH cases.Material & Methods: Medical records of patients with all forms of CAH from 19 adult endocrinology clinics located at six ...